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Inherent Safer Design

Process Intensification for Inherent Hazard Reduction

We evaluate technology routes such as microreactors, flow chemistry and structured reactors to engineer inherent safety into the design

Technical overview

Process Intensification for Inherent
Hazard Reduction

Process intensification is the inherent safer design strategy that replaces conventional batch and stirred tank chemistry with technology routes that are inherently smaller, more uniform and less hazardous. These include microreactors, continuous flow chemistry, structured reactors such as monolithic and packed bed designs, reactive distillation, spinning disc and spinning mesh reactors, and distributed point of use generation of hazardous intermediates. The discipline operates at the concept and technology selection stage of a project, ahead of pilot scale up engineering, which is the operational discipline for moving laboratory chemistry to commercial scale once the technology is selected. Intensification reduces hazardous inventory by typical factors of one hundred to ten thousand times compared to batch, with the corresponding reduction in consequence severity, emergency planning zone, SIL allocation burden and insurance loading. Our evaluation work compares conventional against intensified routes against capital cost, operating cost, schedule, the inherent safety and INSET scores and the Heikkilä index, and then defines a safety case for any novel technology where the commercial reference base is thin.

Process Intensification for Inherent Hazard Reduction Overview
Engineering process

Process Intensification for Inherent Hazard Reduction workflow

Conventional Baseline & Hazard Profile

Characterise the conventional batch / stirred tank baseline, inventory per step, hazard index (Dow F&EI / CEI / Heikkilä ISI), consequence zone distance, SIL allocation burden, document opportunity for inherent hazard reduction.

Intensification Technology Screening

Screen intensification options, microreactor, continuous flow, structured (monolithic / packed bed) reactor, reactive distillation, spinning disc, falling film, membrane reactor, align with CCPS PI guidance and process chemistry feasibility.

Kinetics & Residence Time Compatibility

Verify reaction kinetics fit the intensified residence time envelope, identify mass transfer or heat transfer limitations of conventional route that intensification resolves, quantify exotherm management gains.

Inventory & Consequence Zone Quantification

Quantify inventory reduction (typical 100, 10000× vs batch), recalculate consequence zone distances, emergency planning zone footprint, and COMAH / Seveso threshold quantity position, document SIL allocation reduction.

Capex / Opex / Schedule Trade Off

Compare intensified vs conventional route on capex (smaller equipment, modular construction), opex (utilities, footprint, maintenance), schedule (modular startup), and ISI score, build decision matrix for technology route selection.

Safety Case & Technology Hand Off

Author safety case for novel technology route where commercial reference base is thin, integrate with ISD design basis, hand off selected technology to pilot plant scale up engineering (separate operational discipline) for lab to commercial execution.

Process Intensification for Inherent Hazard Reduction Scope
Scope of work

Every deliverable from basis to handover

Complete Process Intensification for Inherent Hazard Reduction scope covering every calculation, drawing, specification, and construction support activity.

We screen technology routes across batch against continuous, conventional against intensified and conventional against novel
We test microreactor and flow chemistry feasibility through kinetics, residence time and exotherm management
We evaluate structured reactors including monolithic, packed bed, falling film and membrane designs
We screen reactive distillation, spinning disc and other process intensification technologies
We quantify inventory reduction, typically one hundred to ten thousand times against batch, with collapse of the consequence zone
We compare the Heikkilä inherent safety index and the INSET toolkit across intensified and conventional alternatives
We weigh the capital cost, operating cost and schedule trade off, covering modular construction, lower utilities and faster startup
We develop a safety case for novel technology where the commercial reference base is thin
We demonstrate SIL allocation reduction through inventory and consequence reduction
We hand off to pilot plant scale up engineering, a separate operational discipline, once the technology is selected
Engineering outcomes

Outcomes of Process Intensification for Inherent Hazard Reduction

Scale Up Hazard Control Assurance
  • We dramatically reduce inventory at source
  • We improve heat and mass transfer
  • We reduce residence time and runaway potential
  • We strengthen inherent safety
CCPS, DIERS and SCALE Guidelines Defence
  • We work to CCPS inherent safer design and scale up guidance
  • We support COMAH and Seveso inventory reduction
  • We document the safe scale up basis
  • We give you evidence that withstands a regulator review of novel technology
Process Intensification Design Quality
  • We deliver a smaller footprint and cleaner operation
  • We enable faster product changeover
  • We improve quality control
  • We support modular construction
Pilot to Production Scale Up Efficiency
  • We lower capital cost through smaller equipment
  • We reduce operating cost through energy efficiency
  • We support a faster time to market through modularity
  • We support lower insurance loadings
Standards & references

Codes & standards we work to

CCPS Inherently Safer Chemical Processes (3rd Ed., 2009)RSC Process IntensificationIChemE Process Intensification Subject GroupEPSC ISD GuidanceCCPS Conceptual Design GuidelinesHeikkilä Inherent Safety IndexINSET ToolkitStankiewicz and Moulijn PI ReferenceMSIHC Rules 1989 (India)Factories Act 1948 Section 41B (India)CCPS Process Intensification
When to engage

Triggers that signal the need

Concept stage technology selectionAn R and D to commercial route evaluationInventory reduction driven by a COMAH or Seveso thresholdA sustainability or carbon footprint redesignA capacity expansion that challenges conventional scale upA licensor or partner technology evaluation
Industries served

Where Process Intensification for Inherent Hazard Reduction applies

Oil & Gas, Upstream

Wellheads, separators, gas compression, FPSO topsides, produced water systems.

UpstreamOffshoreFPSO
Refineries & Petrochemicals

Distillation columns, reactors, heat exchangers, storage spheres, LPG handling.

RefiningPetrochemical
LNG & Gas Processing

Cryogenic exchangers, liquefaction trains, BOG compressors, storage and sendout.

LNGCryogenic
Specialty Chemicals

Reactive systems, batch reactors, solvent handling, runaway reaction scenarios.

ReactiveBatch
Power Generation

Boilers, HRSGs, steam headers, hydrogen systems, ammonia SCR units.

PowerHydrogen
Pharma & Food

Sterile vessels, CIP/SIP, pressure fermenters, solvent recovery, spray dryers.

PharmaFood & Bev
What we deliver

Tangible deliverables

  • Process intensification opportunity report
  • Technology route comparison matrix covering conventional against intensified
  • Heikkilä inherent safety index and INSET score for each option
  • Inventory and consequence zone reduction quantification
  • Capital cost, operating cost and schedule trade off analysis
  • Safety case for novel technology
  • SIL allocation reduction evidence
  • Technology selection recommendation with an inherent safer design basis
Get Started

Ready to start your project?

Speak with our team to scope an engagement tailored to your facility, regulatory context, and lifecycle stage.